Multiple Gastrointestinal Drug Induced Ulcers Associated with Aspirin and Non-steroidal Anti-inflammatory Drugs: A Case Report and Review of the Literature / 대한소화기내시경학회지
Korean Journal of Gastrointestinal Endoscopy
;
: 379-383, 2009.
Article
in Korean
| WPRIM
| ID: wpr-176802
ABSTRACT
Aspirin and non-steroidal anti-inflammatory drugs (NSAIDs) are widely prescribed drugs, and they are known to be responsible for many cases of gastroduodenal ulcerations by inhibiting prostaglandin synthesis via blocking the cyclo-oxygenase production. Colonic side effects of these drugs are rare, but they are increasingly being reported to be due to the popularization of colonoscopy and the new formulations of drugs such as enteric coated pills or slow release pills. There is currently no consensus for making the clinical diagnosis and administering the proper therapy for drug-induced colonopathy in Korea. We experienced the patient who had multiple colonic ulcers after ingesting large amounts of aspirin and NSAIDs. In near future, we hope to determine the clinical and endoscopic features of drug associated colon injury.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Peptic Ulcer
/
Ulcer
/
Anti-Inflammatory Agents, Non-Steroidal
/
Aspirin
/
Colonoscopy
/
Prostaglandin-Endoperoxide Synthases
/
Colon
/
Consensus
/
Korea
Type of study:
Practice guideline
Limits:
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Korean Journal of Gastrointestinal Endoscopy
Year:
2009
Type:
Article
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