Impact of Obesity on a Chinese Population with Erosive Esophagitis and Barrett's Esophagus
Gut and Liver
;
: 377-382, 2017.
Article
in English
| WPRIM
| ID: wpr-17726
ABSTRACT
BACKGROUND/AIMS:
The aim of this study was to investigate the associations between obesity and erosive esophagitis (EE) or Barrett's esophagus (BE) in a Chinese population.METHODS:
Data from subjects were retrospectively collected from 2006 to 2009. Individuals with BE were identified and age- and sex-matched at a 12 ratio with normal esophagocardial junction and EE patients. The subjects were stratified into two groups the normal weight group and overweight/obesity group (body mass index ≥25 mg/m²) or the normal waist group and abdominal obesity group (waist circumference ≥90 cm for men and ≥80 cm for women).RESULTS:
Overall, 45%, 72%, and 52% were overweight/obese and 23%, 65%, and 18% had abdominal obesity in the normal, EE, and BE groups, respectively. Positive associations were identified between EE and overweight/obesity (odds ratio [OR], 3.14; 95% confidence interval [CI], 1.75 to 5.66) and abdominal obesity (OR, 6.22; 95% CI, 3.34 to 11.57); however, the associations were nonsignificant between BE and overweight/obesity (OR, 1.32; 95% CI, 0.67 to 2.61) or abdominal obesity (OR, 0.73; 95% CI, 0.31 to 1.73). Female BE patients had a significantly increased rate of being overweight/obese.CONCLUSIONS:
Obesity is a contributing factor in EE. The association of BE and obesity was not significant, with the exception of female BE cases.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Barrett Esophagus
/
Gastroesophageal Reflux
/
Retrospective Studies
/
Asian People
/
Esophagitis
/
Obesity, Abdominal
/
Obesity
Type of study:
Observational study
/
Prognostic study
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Gut and Liver
Year:
2017
Type:
Article
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