Skeletal Muscle Metastasis and Elevated beta-HCG Level Secondary to Tongue Cancer: a Case Report and Review of Literature / 대한내과학회지
Korean Journal of Medicine
;
: 719-722, 2015.
Article
in Korean
| WPRIM
| ID: wpr-177416
ABSTRACT
Metastases to skeletal muscle and paraneoplastic syndromes involving beta-human chorionic gonadotropin (HCG) production are an extremely rare manifestation of head and neck squamous cell carcinoma. We report a patient with a beta-HCG-secreting squamous cell carcinoma of the tongue with diffuse metastases involving skeletal muscle. A 47 year old female, who was being treated heavily with palliative chemotherapy for metastatic tongue cancer, was admitted with a palpable thigh mass and pain. A magnetic resonance image showed an intramuscular metastasis in the thigh. Ultrasound-guided biopsy of the thigh mass confirmed metastatic squamous cell carcinoma. She was scheduled for enrollment into a clinical trial; however, a positive serum beta-HCG test was noticed. There was no evidence of pregnancy or a trophoblastic or non-trophoblastic tumor secreting beta-HCG. Finally, she was revealed to have a paraneoplastic syndrome with diffuse metastases and was ultimately referred for palliative care. We review the literature of previously reported cases of an increase of beta-HCG in patients with head and neck cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Palliative Care
/
Paraneoplastic Syndromes
/
Thigh
/
Tongue
/
Trophoblasts
/
Biopsy
/
Tongue Neoplasms
/
Carcinoma, Squamous Cell
/
Muscle, Skeletal
/
Chorionic Gonadotropin, beta Subunit, Human
Limits:
Female
/
Humans
/
Pregnancy
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2015
Type:
Article
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