A Patient with Coexisting Myasthenia Gravis and Lambert-Eaton Myasthenic Syndrome
Journal of Clinical Neurology
;
: 235-237, 2012.
Article
in English
| WPRIM
| ID: wpr-177468
ABSTRACT
BACKGROUND:
The coexistence of myasthenia gravis (MG) and Lambert-Eaton myasthenic syndrome (LEMS) is very rare and remains controversial. CASE REPORT A 48-year-old woman initially presented with noticeable right ptosis and intermittent diplopia. She then developed fluctuating proximal limb weakness and difficulty in swallowing. The serum titer of anti-acetylcholine-receptor antibody was elevated and the edrophonium (Tensilon) test was positive. However, repetitive nerve stimulation revealed abnormalities typical of LEMS. The patient exhibited a good response to treatment with anticholinesterase inhibitors and steroids, and long-term evaluation disclosed that she presented with the clinical, electrophysiological, and immunological characteristics of both diseases.CONCLUSIONS:
The reported clinical and electrophysiological features suggest that this patient was a very rare case of combined MG and LEMS.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Steroids
/
Lambert-Eaton Myasthenic Syndrome
/
Deglutition
/
Diplopia
/
Edrophonium
/
Extremities
/
Myasthenia Gravis
Limits:
Female
/
Humans
Language:
English
Journal:
Journal of Clinical Neurology
Year:
2012
Type:
Article
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