The Study of Dose Incremental Regimen for Narrow-Band UVB Phototherapy in Psoriatic patients / 대한피부과학회지
Korean Journal of Dermatology
;
: 671-675, 2001.
Article
in Korean
| WPRIM
| ID: wpr-177501
ABSTRACT
BACKGROUND:
Narrow-band UVB phototherapy using 311+/-2nm wavelength is in widespread use due to its greater efficacy and, possibly, safety compared with broad-band UVB sources. However, its optimal dose increment regimen is not determined.OBJECTIVE:
We performed narrow-band UVB(NBUVB) phototherapy to compare clinical efficacy between fixed and 20% incremental regimen in Korean psoriasis patients.METHODS:
Twenty four psoriasis patients received narrow-band UVB phototherapy. Among them, fifteen patients received fixed regimen and nine patients, 20% incremental regimen. We categorized each patient into clearing, improvement, or failure groups based on the therapeutic efficacy, measured the PASI score every two weeks and calculated cumulative dose of narrow-band UVB.RESULTS:
We found no statistically significant difference between two regimen. However, there is a tendency that irradiation number and duration of treatment are smaller in 20% incremental regimen but, in terms of cumulative dose, fixed incremental regimen is better than 20%.CONCLUSION:
These results suggests that 20% incremental regimen may clear psoriasis faster than fixed but that the latter regimen may be equally effective as it requires slighty more treatment sessions at a lower cumulative dose.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phototherapy
/
Psoriasis
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
2001
Type:
Article
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