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The Study of Dose Incremental Regimen for Narrow-Band UVB Phototherapy in Psoriatic patients / 대한피부과학회지
Korean Journal of Dermatology ; : 671-675, 2001.
Article in Korean | WPRIM | ID: wpr-177501
ABSTRACT

BACKGROUND:

Narrow-band UVB phototherapy using 311+/-2nm wavelength is in widespread use due to its greater efficacy and, possibly, safety compared with broad-band UVB sources. However, its optimal dose increment regimen is not determined.

OBJECTIVE:

We performed narrow-band UVB(NBUVB) phototherapy to compare clinical efficacy between fixed and 20% incremental regimen in Korean psoriasis patients.

METHODS:

Twenty four psoriasis patients received narrow-band UVB phototherapy. Among them, fifteen patients received fixed regimen and nine patients, 20% incremental regimen. We categorized each patient into clearing, improvement, or failure groups based on the therapeutic efficacy, measured the PASI score every two weeks and calculated cumulative dose of narrow-band UVB.

RESULTS:

We found no statistically significant difference between two regimen. However, there is a tendency that irradiation number and duration of treatment are smaller in 20% incremental regimen but, in terms of cumulative dose, fixed incremental regimen is better than 20%.

CONCLUSION:

These results suggests that 20% incremental regimen may clear psoriasis faster than fixed but that the latter regimen may be equally effective as it requires slighty more treatment sessions at a lower cumulative dose.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Phototherapy / Psoriasis Limits: Humans Language: Korean Journal: Korean Journal of Dermatology Year: 2001 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Phototherapy / Psoriasis Limits: Humans Language: Korean Journal: Korean Journal of Dermatology Year: 2001 Type: Article