A Case of Multiple Myeloma with Biclonal (IgG-K and IgA-K) M-proteins / 대한임상병리학회지
Korean Journal of Clinical Pathology
;
: 310-314, 1998.
Article
in Korean
| WPRIM
| ID: wpr-177889
ABSTRACT
Two M-protein peaks in serum protein electrophoresis are rarely present in patients with plasma cell discrasia. We describe a 72-year-old male patient with multiple myeloma secreting biclonal M-proteins, which were confirmed by immunofixation. Immunoelectrophoresis has some difficulties to dectect M components when a very small amount of M-protein develops an equivocally abnormal precipitation arc. In this case, serum protein electrophoresis revealed two M peaks, one in beta and the other in gamma globulin region. An immunoelectrophoresis revealed unequivocally abnormal precipitation arcs in IgA and K light chain regions, but the arc in IgG region was equivocal. We performed an immunofixation and confirmed biclonal gammopathy, IgA-K and IgG-K types. This result supports the view that immunofixation is an useful confirmatory test when immunoelectrophoresis results are equivocal.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plasma Cells
/
Gamma-Globulins
/
Immunoglobulin A
/
Immunoglobulin G
/
Myeloma Proteins
/
Immunoelectrophoresis
/
Electrophoresis
/
Multiple Myeloma
Limits:
Aged
/
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Clinical Pathology
Year:
1998
Type:
Article
Similar
MEDLINE
...
LILACS
LIS