Successful Treatment of Disseminated Fusariosis with Liposomal Amphotericin B and Voriconazole in a Child Undergoing Chemotherapy / 대한소아혈액종양학회지
Korean Journal of Pediatric Hematology-Oncology
; : 330-334, 2005.
Article
in Ko
| WPRIM
| ID: wpr-178949
Responsible library:
WPRO
ABSTRACT
Fusarium species are common soil saprophytes and plant pathogens. In humans, several species have been recognized as agents of superficial infections. Disseminated Fusariosis have been increasingly described in immunocompromised patients, especially in neutropenic patients. The prognosis is very poor despites antifungal therapy. This is the report of Fusarium oxysporum infection in a 6-year-old patient with relapsed acute leukemia and prolonged neutropenia. The patient presented with persistent fever and multiple erythematous papules with central necrosis or vesicle. Fuasrium oxysporum was isolated and cultured from a skin biopsy specimen. Initially, the patient failed to respond to conventional amphotericin B but recovered after treatment was switched to liposomal amphotericin B and voriconazole.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Plants
/
Prognosis
/
Skin
/
Soil
/
Biopsy
/
Leukemia
/
Amphotericin B
/
Immunocompromised Host
/
Drug Therapy
/
Fever
Type of study:
Prognostic_studies
Limits:
Child
/
Humans
Language:
Ko
Journal:
Korean Journal of Pediatric Hematology-Oncology
Year:
2005
Type:
Article