Short-Term Effect of High Dose of Vitamin C on Coronary Flow Velocity and Coronary Flow Reserve in Healthy Young Non-Smoker Men
Journal of the Korean Society of Echocardiography
;
: 78-82, 2004.
Article
in Korean
| WPRIM
| ID: wpr-179215
ABSTRACT
BACKGROUND AND OBJECTIVES:
Vitamin C, water-soluble antioxidant, has been reported to restore coronary microcirculatory responsiveness and impaired coronary flow reserve in smokers. However, the effect of high dose of vitamin C on coronary circulation is unclear in nonsmokers.METHODS:
We used transthoracic echocardiography to measure the coronary flow reserve, an integrated measure of coronary flow in 20 male healthy nonsmokers (26+/-3 years) before and after administration of the high dose of vitamin C.RESULTS:
The coronary peak diastolic velocity was increased by 14.8% after administration of antioxidant vitamin C, whereas the coronary flow reserve did not changed.CONCLUSION:
High dose of vitamin C acutely increases the coronary flow velocity without restoration of coronary flow reserve in male healthy nonsmokers.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Ascorbic Acid
/
Vitamins
/
Echocardiography
/
Coronary Circulation
/
Lobeline
Limits:
Humans
/
Male
Language:
Korean
Journal:
Journal of the Korean Society of Echocardiography
Year:
2004
Type:
Article
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