Correlation Between NT-proBNP and Pulmonary Arterial Pressure in COPD Patients / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases
;
: 346-352, 2007.
Article
in Korean
| WPRIM
| ID: wpr-179432
ABSTRACT
BACKGROUND:
Pulmonary hypertension is one of the cardiovascular complications of in COPD. However, a diagnosis of pulmonary hypertension requires an invasive test, such as right heart catheterization. NT-proBNP is a cardiac hormone that is elevated when a cardiac volume or pressure overload is present. It was hypothesized that NT-proBNP might play a role in detecting of pulmonary hypertension in COPD patients.METHOD:
The 31 COPD patients, who underwent all of NT-proBNP, echocardiography, and spirometry in Seoul National University Bundang Hospital during the period from November 2003 to July 2005, were retrospectively analyzed.RESULT:
Of the 31 COPD patients, 9 patients had pulmonary hypertension. A significant positive correlation was observed between the NT-proBNP and pulmonary arterial pressure (r=0.589, p=0.002). However, there was no significant correlation observed between the FEV(1) and NT-proBNP and FEV(1) and pulmonary arterial pressure.CONCLUSION:
NT-proBNP might indicate the presence of pulmonary hypertension in COPD patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Spirometry
/
Echocardiography
/
Cardiac Catheterization
/
Cardiac Volume
/
Retrospective Studies
/
Pulmonary Disease, Chronic Obstructive
/
Diagnosis
/
Cardiac Catheters
/
Arterial Pressure
/
Seoul
Type of study:
Diagnostic study
/
Observational study
Limits:
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Tuberculosis and Respiratory Diseases
Year:
2007
Type:
Article
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