Reversible Symptomatic Myocarditis Induced by All-Trans Retinoic Acid Administration during Induction Treatment of Acute Promyelocytic Leukemia: Rare Cardiac Manifestation as a Retinoic Acid Syndrome
Journal of Cardiovascular Ultrasound
;
: 95-98, 2011.
Article
in English
| WPRIM
| ID: wpr-179798
ABSTRACT
Treatment by All-trans retinoic acid (ATRA) followed by anthracycline-AraC chemotherapy has improved the outcome of acute promyelocytic leukemia. ATRA is usually well tolerated, but a few major side effects can be observed. Retinoic acid syndrome (RAS) often occurs during the induction chemotherapy of acute promyelocytic leukemia. A pericardial effusion is a common cardiac manifestation but myocarditis has been rarely documented. Here we reports a very rare case of fully recovered myocarditis as a result of RAS related to ATRA administration during induction treatment of acute promyelocytic leukemia which documented by echocardiographic evidence.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pericardial Effusion
/
Tretinoin
/
Leukemia, Promyelocytic, Acute
/
Induction Chemotherapy
/
Myocarditis
Type of study:
Diagnostic study
Language:
English
Journal:
Journal of Cardiovascular Ultrasound
Year:
2011
Type:
Article
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