Long-Term Recurrence Rates of Peptic Ulcers without Helicobacter pylori
Gut and Liver
;
: 719-725, 2016.
Article
in English
| WPRIM
| ID: wpr-179857
ABSTRACT
BACKGROUND/AIMS:
The purpose of this study is to investigate the recurrence rate of peptic ulcer disease (PUD) over a long follow-up period with PUD patients without Helicobacter pylori.METHODS:
We retrospectively reviewed patients diagnosed with PUD on endoscopy and divided them into two groups a H. pylori-negative group (HP-negative group), and a group of patients with untreated H. pylori (HP noneradicated group). We compared the recurrence rates of PUD in these two groups and analyzed the factors that affected ulcer recurrence.RESULTS:
Total of nine hospitals in Korea participated, and a total of 1,761 patients were retrospectively reviewed. The HP-negative group included 553 patients, and the HP noneradicated group included 372 patients. The 5-year cumulative probabilities of PUD recurrence were 36.4% in the HP-negative group and 43.8% in the HP noneradicated group (p=0.113). The factors that were found to affect recurrence in the HP-negative group were elder, male, and comorbid chronic kidney disease.CONCLUSIONS:
The 5-year cumulative probability of PUD recurrence without H. pylori infection after a long-term follow-up was 36.4% and the factors that affected recurrence were elder, male, and comorbid chronic kidney disease.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Peptic Ulcer
/
Recurrence
/
Ulcer
/
Retrospective Studies
/
Follow-Up Studies
/
Helicobacter pylori
/
Helicobacter
/
Endoscopy
/
Renal Insufficiency, Chronic
/
Korea
Type of study:
Observational study
/
Prognostic study
Limits:
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
Gut and Liver
Year:
2016
Type:
Article
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