PCR Prevalence and Risk Factors of Hepatitis C Virus Infection in the Adult Population of Ulsan
Journal of the Korean Academy of Family Medicine
;
: 364-373, 1998.
Article
in Korean
| WPRIM
| ID: wpr-180679
ABSTRACT
BACKGROUND:
Liver disease is an important public health problem in Korea. The aim of this study was to estimate the prevalence of hepatitis C virus antibody(anti-HCV) in the adult population of Ulsan and to identify risk factors for HCV infection by case centre study.METHODS:
The anti-HCV test was performed in 10,140 adults older than 20 years of age who underwent a general medical checkup in Ulsan University Hospital, Health Promotior Center from January 1997 to November 1997. 33 cases and 99 controls matched for age and sex with a 1 3 ratio of cases to controls were enrolled. The cases were defined as positive anti-HCV and positive HCV-RNA whereas the controls were negative anti-HCV negative HBsAg and ALT < OR = 40. Exposure data were obtained by self-administered questionnaire.RESULTS:
The overall prevalence of anti-HCV was 1.3%(95% CI 1.1-1.5) and the positive predictive value of 3rd generation anti-HCV ELISA was 34%. Thus, true prevalence of HCV infection was 0.45%. Only history of transfusion was significantly associated with anti-HCV infection.CONCLUSIONS:
The overall prevalence of anti-HCV was 1.3% and true prevalence of HCV infection was 0.45% in the adult population of Ulsan. Transfusion was the major route of transmission of HCV but the risk will likely reduce.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Enzyme-Linked Immunosorbent Assay
/
Polymerase Chain Reaction
/
Public Health
/
Prevalence
/
Surveys and Questionnaires
/
Risk Factors
/
Hepatitis C
/
Hepacivirus
/
Hepatitis
/
Hepatitis B Surface Antigens
Type of study:
Etiology study
/
Prevalence study
/
Prognostic study
/
Risk factors
Limits:
Adult
/
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Journal of the Korean Academy of Family Medicine
Year:
1998
Type:
Article
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