Comparison of D-PUVA with Conventional PUVA in the Treatment of Korean Psoriasis Patients / 대한피부과학회지
Korean Journal of Dermatology
;
: 275-279, 1998.
Article
in Korean
| WPRIM
| ID: wpr-180947
ABSTRACT
BACKGROUND:
PUVA photochemotherapy has been accepted as an effective mode of treatment for psoriasis. Many combination therapies have been tried to reduce the possible adverse effects of long-term exposure to UV radiation.OBJECTIVE:
This study was performed to compare calcipotriol-PUVA combination therapy(D-PUVA) with conventional PUVA in the treatment of Korean psoriasis patients.METHODS:
We treated 38 Korean psoriasis patients with conventional PUVA and 12 with D-PUVA. We compared the total number, duration and total UVA dose of PUVA therapy to reach grade 4 between the two groups. We categorized each patient into clearing, improvement, or failure groups based on the therapeutic efficacy, and measured the PASI score at each of the patients visits.RESULTS:
The total cumulative dose of D-PUVA phototherapy was significantly smaller than PUVA phototherapy.CONCLUSION:
Combining PUVA with a vitamin D analogue, calcipotriol, in the treatment of psoriasis may lead to lowering the risk of long-term exposure to UV radiation with higher efficacy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Phototherapy
/
Photochemotherapy
/
Psoriasis
/
PUVA Therapy
/
Vitamin D
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
1998
Type:
Article
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