Therapeutic Effect of Minocycline on Confluent and Reticulated Papillomatosis / 대한피부과학회지
Korean Journal of Dermatology
;
: 204-209, 1998.
Article
in Korean
| WPRIM
| ID: wpr-180957
ABSTRACT
BACKGROUND:
Confluent and reticulate papillomatosis(CRP) of Gougerot and Carteaud is an uncommon disorder of unknown cause for which a variety of treatments have been proposed.OBJECTIVE:
We attempted to evaluate the therapeutic effect of oral minocycline for CRP.METHOD:
Nine patients(age range, 14 to 38; mean age, 21years) with CRP were included in this study. They took minocycline 100mg daily. The therapeutic effect was evaluated weekly by 5 scoring systems according to the percentage clearing of the skin lesion poor (score 1), 95%.RESULTS:
Two out of 9 patients showed complete clearing(score 5) of the skin lesions within 2 weeks. Seven patients revealed incomplete clearing(score 4) within 3 to 8 weeks. The mean scoring for 9 CRP patients was 4.2. Recurrences were noted in two patients at 24 and 26 months, respectively, but they responded to re-treatment with minocycline. The patients did not show any adverse reactions apart from two patients who developed mild pruritus.CONCLUSION:
We recommend minocycline as the first choice of treatment for CRP because minocycline is safe, economic and effective.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Papilloma
/
Pruritus
/
Recurrence
/
Skin
/
Minocycline
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
1998
Type:
Article
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