Revisiting the Pre-transfusion Test: A Case of Acute Hemolytic Transfusion Reaction due to Multiple Alloantibodies of Anti-E, Anti-c, Anti-Jk(b) / 대한수혈학회지
Korean Journal of Blood Transfusion
;
: 170-176, 2017.
Article
in Korean
| WPRIM
| ID: wpr-18194
ABSTRACT
We report a case of acute hemolytic transfusion reaction due to multiple alloantibodies. A 41-year-old male with multiple histories of transfusion was admitted for jaundice and oliguria after receiving two units of red blood cells in a local clinic. He showed acute renal failure and disseminated intravascular coagulation. Direct Coombs test was negative and antibody screening test showed strong positive results. Anti-E, anti-c, and anti-Jk(b) antibodies were identified in two panels of unexpected antibody assays. Acute hemolytic transfusion was diagnosed, and he was discharged after 1 month of supportive treatment. Unexpected antibody detection tests, including the antiglobulin phase, should be performed to prevent adverse transfusion reactions by unexpected antibodies. Better precision and quality control are necessary when performing pre-transfusion tests.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Oliguria
/
Quality Control
/
Coombs Test
/
Mass Screening
/
Disseminated Intravascular Coagulation
/
Erythrocytes
/
Acute Kidney Injury
/
Transfusion Reaction
/
Isoantibodies
/
Jaundice
Type of study:
Prognostic study
/
Screening study
Limits:
Adult
/
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Blood Transfusion
Year:
2017
Type:
Article
Similar
MEDLINE
...
LILACS
LIS