Effect of bamboo salt on human gingival fibroblasts / 대한구강보건학회지
Journal of Korean Academy of Oral Health
;
: 90-94, 2014.
Article
in Korean
| WPRIM
| ID: wpr-182190
ABSTRACT
OBJECTIVES:
To evaluate the anti-inflammatory and cytotoxic activities of bamboo salt.METHODS:
Cytotoxicity of bamboo salt and bay salt (0.01%, 0.1%, and 1%) was evaluated using MTT assay. In addition, secretion of the pro-inflammatory cytokines interleukin (IL)-1beta and IL-6 from human gingival fibroblasts (HGFs) was measured after application of 0.01% and 0.1% concentrations by using real-time polymerase chain reaction.RESULTS:
Bamboo salt and bay salt at 1% concentration were cytotoxic to HGFs at 24 h; however, no such effect was observed at 0.01% or 0.1%. Bamboo salt showed a relatively low inhibitory effect. IL-1beta secretion was inhibited by a 0.1% solution of bamboo salt. IL-6 secretion was inhibited by both bamboo salt and bay salt at 0.1% concentration.CONCLUSIONS:
The above results suggest that bamboo salt inhibits the release of IL-1beta and IL-6 from HGFs. Thus, bamboo salt may be a useful material for gingival inflammation.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Cytokines
/
Interleukins
/
Interleukin-6
/
Bays
/
Real-Time Polymerase Chain Reaction
/
Fibroblasts
/
Inflammation
Limits:
Humans
Language:
Korean
Journal:
Journal of Korean Academy of Oral Health
Year:
2014
Type:
Article
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