A Case of Rectal Cancer in a Patient with X-linked Agammagloubulinemia / 대한소화기내시경학회지
Korean Journal of Gastrointestinal Endoscopy
;
: 360-363, 2010.
Article
in Korean
| WPRIM
| ID: wpr-18223
ABSTRACT
X-linked agammaglobulinemia (XLA) is a primary immunodeficiency disorder caused by germline mutation of the Bruton tyrosine kinase (BTK) gene. Most of the patients diagnosed X-LA suffer from recurrent infections of the respiratory and gastrointestinal tracts. Increased risk of malignancy in X-LA patients include lymphoma, gastric cancer, colorectal cancer. We report a case of 32-years-old male patient with X-linked agammagolbulinemia and rectal cancer. Agammaglobulinemia was diagnosed at 13 years old. He underwent colonoscopy for hematochezia. An ulceroinfiltrative mass was found during colonscopy and biopsy revealed moderately differentiated adenocarcinoma. Subsequently, he underwent a anterior resection.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Rectal Neoplasms
/
Stomach Neoplasms
/
Biopsy
/
Protein-Tyrosine Kinases
/
Colorectal Neoplasms
/
Adenocarcinoma
/
Colonoscopy
/
Germ-Line Mutation
/
Agammaglobulinemia
/
Genetic Diseases, X-Linked
Limits:
Humans
/
Male
Language:
Korean
Journal:
Korean Journal of Gastrointestinal Endoscopy
Year:
2010
Type:
Article
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