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A Solitary Colonic Neurofibroma in a Patient without Neurofibromatosis / 대한소화기내시경학회지
Korean Journal of Gastrointestinal Endoscopy ; : 44-47, 2008.
Article in Korean | WPRIM | ID: wpr-182653
ABSTRACT
Neurofibromas are usually manifestations of neurofibromatosis type 1 (Nf1). There are usually multiple lesions on presentation. Solitary neurofibromas of the colon are extremely rare. A 34-year-old Asian male came to our hospital for non-specific findings, except for a complaint of loose stools for 2 months. A colonoscopy was performed. A sessile polyp 0.4 cm in diameter was detected at the sigmoid colon. Microscopically, a biopsy from the polyp showed proliferation of spindle cells in the mucosa, myxoid changes and infiltration of inflammatory cells. Immunohistochemical staining was positive for S-100 protein. The above morphological and immunohistochemical characteristics were consistent with a diagnosis of a neurofibroma. Only 13 cases of isolated colonic neurofibromatosis without Nf1 have been documented in the literature. We report this case as an isolated neurofibroma of the colon is even a rarer manifestation, and only three cases have been published in the clinical literature.
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Full text: Available Index: WPRIM (Western Pacific) Main subject: Polyps / Porphyrins / Colon, Sigmoid / Biopsy / S100 Proteins / Colonoscopy / Neurofibromatosis 1 / Neurofibromatoses / Colon / Asian People Limits: Adult / Humans / Male Language: Korean Journal: Korean Journal of Gastrointestinal Endoscopy Year: 2008 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Polyps / Porphyrins / Colon, Sigmoid / Biopsy / S100 Proteins / Colonoscopy / Neurofibromatosis 1 / Neurofibromatoses / Colon / Asian People Limits: Adult / Humans / Male Language: Korean Journal: Korean Journal of Gastrointestinal Endoscopy Year: 2008 Type: Article