Effects of Sertraline on Memory Function of Patients with Posttraumatic Stress Disorder / 대한정신약물학회지
Korean Journal of Psychopharmacology
;
: 346-353, 2004.
Article
in Korean
| WPRIM
| ID: wpr-183875
ABSTRACT
OBJECTIVE:
This study was conducted to evaluate effects of sertraline treatment on symptoms and memory function of posttraumatic stress disorder (PTSD).METHODS:
Thirty Vietnam veterans were collected for this study, among whom fifteen were PTSD patients and fifteen were combat control subjects. We used Mississippi Scale for Combat-Related PTSD, Combat Exposure Scale (CES), Hamilton Depression Rating Scale (HDRS) and Clinician Administered PTSD Scale (CAPS). Digit Span, Paired Association Learning Test (PALT) and Rey- Osterreith Complex Figure Test (CFT) were assessed for memory function. We evaluated HDRS, CAPS and memory function tests at baseline, 2-week and 6-week intervals with each subjects.RESULTS:
There were significant differences between PTSD and Non-PTSD veterans in Mississippi Scale for Combat-Related PTSD, CES, HDRS and CAPS. Significant difference was found in memory function tests between PTSD and Non-PTSD veterans. PTSD veterans showed significant improvement in HDRS and CAPS at 2-week and 6-week and in memory function tests at 6-week of sertraline treatment. There was no significant correlation between symptoms and memory function.CONCLUSION:
These results suggest that sertraline improve symptoms and memory function of PTSD. There was no significant correlation between PTSD sysmtoms and memory function.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Association Learning
/
Stress Disorders, Post-Traumatic
/
Veterans
/
Vietnam
/
Mississippi
/
Sertraline
/
Depression
/
Memory
Limits:
Humans
Country/Region as subject:
North America
/
Asia
Language:
Korean
Journal:
Korean Journal of Psychopharmacology
Year:
2004
Type:
Article
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