Prognostic Significance of Volume-Based PET Parameters in Cancer Patients
Korean Journal of Radiology
;
: 1-12, 2013.
Article
in English
| WPRIM
| ID: wpr-184550
ABSTRACT
Accurate prediction of cancer prognosis before the start of treatment is important since these predictions often affect the choice of treatment. Prognosis is usually based on anatomical staging and other clinical factors. However, the conventional system is not sufficient to accurately and reliably determine prognosis. Metabolic parameters measured by 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) have the potential to provide valuable information regarding prognosis and treatment response evaluation in cancer patients. Among these parameters, volume-based PET parameters such as metabolic tumor volume and total lesion glycolysis are especially promising. However, the measurement of these parameters is significantly affected by the imaging methodology and specific image characteristics, and a standard method for these parameters has not been established. This review introduces volume-based PET parameters as potential prognostic indicators, and highlights methodological considerations for measurement, potential implications, and prospects for further studies.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Predictive Value of Tests
/
Radiopharmaceuticals
/
Fluorodeoxyglucose F18
/
Positron-Emission Tomography
/
Tumor Burden
/
Glycolysis
/
Neoplasm Staging
/
Neoplasms
Type of study:
Prognostic study
Limits:
Humans
Language:
English
Journal:
Korean Journal of Radiology
Year:
2013
Type:
Article
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