Unusual Skin tuberculosis following BCG Vaccination / 대한피부과학회지

ABSTRACT

A 14-year-old female patient was seen with a nodular lesion on her left shoulder which developed one month after BCG vaccination. Physical examination revealed a thumb tip sized, irregular surfaced, erythematous scar-like plaque on the left shoulder, and a 2.5cm diameter, movable, subcutaneous nodule without surface change on the left axilla. Histopathologic examination of the plaque on the left shoulder and axillary nodule showed tubercles composed of mononuclear cells, epithelioid cells and giant cells of the Langhans type in the dermis. Caseation necrosis within the typical tubercles was noted. Prominent resolution of the lesion was observed 4 months after oral medication with isoniazid and ethambutol. The subcutaneous axillary nodule which developed after BCG vaccination was thought to be an unusual manifestation of skin tuberculosis.