A Case of Atrial Fibrillation Induced by Infliximab in a Patient with Rheumatoid Arthritis
Journal of Rheumatic Diseases
;
: 302-305, 2011.
Article
in Korean
| WPRIM
| ID: wpr-186127
ABSTRACT
Infliximab, a chimeric monoclonal immunoglobulin antibody to tumor necrosis factor (TNF)-alpha is widely used in the treatment of rheumatoid arthritis (RA). The commonly reported cardiac side effects of infliximab include exacerbation of congestive heart failure, hypotension, and syncope. Cardiac arrhythmia and conduction disturbances have been reported only rarely in a few case reports and to the best of our knowledge, there are no previous reports on the occurrence of atrial fibrillation secondary to infliximab use in RA patients. Here, we report a case of acute atrial fibrillation with rapid ventricular response that occurred 24 hr after first dose of infliximab in a 55-year-old female patient with RA, who recovered to sinus rhythm after pharmacologic management.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Arrhythmias, Cardiac
/
Arthritis, Rheumatoid
/
Atrial Fibrillation
/
Syncope
/
Immunoglobulins
/
Tumor Necrosis Factor-alpha
/
Infliximab
/
Heart Failure
/
Hypotension
/
Antibodies, Monoclonal
Limits:
Female
/
Humans
Language:
Korean
Journal:
Journal of Rheumatic Diseases
Year:
2011
Type:
Article
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