Studies on the Transmissibility of Pathogenic-Organisms to Liver by Larvae of Liver Fluke and Hookworm

ABSTRACT

In order to confirm whether the migrating larvae of parasites could carry pathogenic organisms into liver and cause hepatitis, a series of experiments has been carried out. The summary of the results is as follows 1. Clonorchis sinensis A few of the excysted larvae of Clonorchis sinensis penetrated into the peritoneal cavity, but they could not penetrate the liver tissues. The artificially introduced Clonorchis sinensis in the tissues were all destroyed within 3-5 days. There was no manifestation of diffuse inflammatory changes due to the inoculation of the parasites, though the sampled micro-organisms, Staphylococcus aureus, were confirmed from the surrounding area. 2. Hookworm The larvae carried pathogenic organisms to liver tissues either by cutaneous or oral infection, but there was no manifestation of hepatitis due to the micro-organisms In conclusion, it is indicated that liverfluke and hookworm may transmit pathogenic organisms to the liver during their migration.