A Case of Reversible Posterior Leukoencephalopathy Syndrome in Patient with Chronic Renal Failure / 대한신장학회잡지
Korean Journal of Nephrology
;
: 127-131, 2001.
Article
in Korean
| WPRIM
| ID: wpr-186219
ABSTRACT
A Reversible Posterior Leukoencephalopathy Syndrome(RPLS) consists of neurologic symptoms and signs - headache, consciousness change, seizure, visual impairment - and brain imaging finding showing brain(espicially white matter) edema usually involving the posteior parietal-temporal-occipital areas. The causes are thought to be hypertensive encephalopathy, pre-eclampsia or eclampsia, renal failure with fluid overload and immunosuppressive agents such as cyclosporin A or FK506. RPLS may usually reversible if treated early by decreasing blood pressure and discontinuing offending drugs. A 23-year-old man had been hemodialyzed with chronic renal failure for two years. His blood pressure elevated to 240/150mmHg 3 days before admission and he complained of severe headache, vomiting, and total visual loss at the day of admission. Brain T2-weighted MRI imaging showed increased signal intensity involving the both parietal, posterior temporal, and occipital lobes. After antihypertensive and dexamethason treatment, a follow-up brain MRI performed on 7 days after admission showed nearly normalized findings and all symptoms including visual loss were recovered completely in one week.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pre-Eclampsia
/
Seizures
/
Vomiting
/
Blood Pressure
/
Brain
/
Magnetic Resonance Imaging
/
Blindness
/
Follow-Up Studies
/
Tacrolimus
/
Cyclosporine
Type of study:
Observational study
/
Prognostic study
Limits:
Female
/
Humans
/
Pregnancy
Language:
Korean
Journal:
Korean Journal of Nephrology
Year:
2001
Type:
Article
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