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Immune-mediated Liver Injury in Hepatitis B Virus Infection
Immune Network ; : 191-198, 2015.
Article in English | WPRIM | ID: wpr-186451
ABSTRACT
Hepatitis B virus (HBV) is responsible for approximately 350 million chronic infections worldwide and is a leading cause of broad-spectrum liver diseases such as hepatitis, cirrhosis and liver cancer. Although it has been well established that adaptive immunity plays a critical role in viral clearance, the pathogenetic mechanisms that cause liver damage during acute and chronic HBV infection remain largely known. This review describes our current knowledge of the immune-mediated pathogenesis of HBV infection and the role of immune cells in the liver injury during hepatitis B.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Fibrosis / Hepatitis B virus / Adaptive Immunity / Hepatitis / Hepatitis B / Liver / Liver Diseases / Liver Neoplasms Language: English Journal: Immune Network Year: 2015 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Fibrosis / Hepatitis B virus / Adaptive Immunity / Hepatitis / Hepatitis B / Liver / Liver Diseases / Liver Neoplasms Language: English Journal: Immune Network Year: 2015 Type: Article