Immune-mediated Liver Injury in Hepatitis B Virus Infection
Immune Network
;
: 191-198, 2015.
Article
in English
| WPRIM
| ID: wpr-186451
ABSTRACT
Hepatitis B virus (HBV) is responsible for approximately 350 million chronic infections worldwide and is a leading cause of broad-spectrum liver diseases such as hepatitis, cirrhosis and liver cancer. Although it has been well established that adaptive immunity plays a critical role in viral clearance, the pathogenetic mechanisms that cause liver damage during acute and chronic HBV infection remain largely known. This review describes our current knowledge of the immune-mediated pathogenesis of HBV infection and the role of immune cells in the liver injury during hepatitis B.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Fibrosis
/
Hepatitis B virus
/
Adaptive Immunity
/
Hepatitis
/
Hepatitis B
/
Liver
/
Liver Diseases
/
Liver Neoplasms
Language:
English
Journal:
Immune Network
Year:
2015
Type:
Article
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