Two Cases of Chronic Acquired Hepatocerebral Degeneration with Parkinsonian Symptoms
Journal of the Korean Neurological Association
;
: 579-584, 1999.
Article
in Korean
| WPRIM
| ID: wpr-18646
ABSTRACT
Chronic acquired hepatocerebral degeneration (CAHD) is a progressive or episodic neurologic syndrome that occurs occasionally in patients who have chronic liver disease or portocaval shunt. The clinical features of CAHD include action and postural tremors, generalized chorea, asterixis, myoclonus, dystonia, resting tremor, gait ataxia, and variable impairments of intellectual function. We experienced 2 cases of CAHD with unusual neurologic manifestations, which were hypokinetic parkinsonian symptoms. Both cases had a history of liver cirrhosis and the same symptoms. They had masked faces, cogwheel rigidiy in both wrists, slurred speech, tongue tremor, bradykinesia, and gait ataxia. They had normal mental status and no pathologic reflex. Brain MRI showed abnormal, increased signal on T1-weighted images in the globus pallidus and mesencephalon bilaterally. The hypokinetic parkinsonian symptoms disappeared when given doses levodopa.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Reflex
/
Tongue
/
Tremor
/
Wrist
/
Brain
/
Mesencephalon
/
Magnetic Resonance Imaging
/
Levodopa
/
Chorea
/
Hypokinesia
Type of study:
Controlled clinical trial
/
Diagnostic study
Limits:
Humans
Language:
Korean
Journal:
Journal of the Korean Neurological Association
Year:
1999
Type:
Article
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