Relations between Long-term Glycemic Control and Postoperative Wound and Infectious Complications after Total Knee Arthroplasty in Type 2 Diabetics
Clinics in Orthopedic Surgery
;
: 118-123, 2013.
Article
in English
| WPRIM
| ID: wpr-186819
ABSTRACT
BACKGROUND:
The authors examined whether poor preoperative glucose control, as indicated by the hemoglobin A1c (HbA1c) level of more than 8%, is associated with postoperative wound and infectious complications in diabetic patients that have undergone total knee arthroplasty (TKA).METHODS:
One hundred and sixty-seven TKAs performed in 115 patients with type 2 diabetes mellitus, from January 2001 through March 2007, were retrospectively reviewed. Logistic regression was used to identify the variables that had a significant effect on the risk of wound complications or early deep infection. The variables considered were age, gender, body mass index, comorbidities, operation time, antibiotic-impregnated cement use, amount of blood transfusion, close suction drain use, duration of diabetes, method of diabetes treatment, diabetes complications, and preoperative HbA1c level.RESULTS:
The overall incidence of wound complications was 6.6% (n = 11) and there were seven cases (4.2%) of early postoperative deep infection. Logistic regression revealed that the independent risk factors of wound complications were preoperative HbA1C > or = 8% (odds ratio [OR], 6.07; 95% confidence interval [CI], 1.12 to 33.0) and operation time (OR, 1.01; 95% CI, 1.00 to 1.03). No variable examined was found to be significantly associated with the risk of early postoperative deep infection.CONCLUSIONS:
Poorly controlled hyperglycemia before surgery may increase the incidence of wound complications among diabetic patients after TKA.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Surgical Wound Infection
/
Blood Glucose
/
Glycated Hemoglobin
/
Logistic Models
/
Incidence
/
Retrospective Studies
/
Arthroplasty, Replacement, Knee
/
Diabetes Mellitus, Type 2
/
Glucose
/
Hypoglycemic Agents
Type of study:
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Aged
/
Aged80
/
Female
/
Humans
/
Male
Language:
English
Journal:
Clinics in Orthopedic Surgery
Year:
2013
Type:
Article
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