A Case of Vitreous Amyloidosis

ABSTRACT

PURPOSE: To report a case of vitreous amyloidosis. METHODS: A 51-year old male presented with bilateral floater and decreased visual acuity of 3 months duration. Small white dots attached to the posterior lens surface were observed on slit lamp examination. The vitreous opacity, which connected with the small white dots to the posterior lens surface, were observed on funduscopic examination, and multiple hyperechoic plaques in the vitreous cavity on B-scan. The pars plana vitrectomy was performed. RESULTS: The aspirate of the pars plana vitrectomy was stained with Congo red and observed with light microscope, and polarized light. Electron microscopy was also performed. The vitreous smear stained with Congo red showed greenish dichroism and birefringent nature with polarized light and fine fibrillar nature of amyloid material was noted on electron microscopy. CONCLUSIONS: To our knowledge, this is the first Korean report of vitreous amyloidosis. The authors diagnosed vitreous amyloidosis that developed in a 51-year-old male patient. The diagnosis was confirmed by light microscope, polarized light and electron microscope.