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Effect of cassia cinnamon intake on improvement of the glycemic response: An updated meta-analysis: Focus on preparation of dehydrated powder and water extract / 한국영양학회지
Journal of Nutrition and Health ; : 437-446, 2017.
Article in Korean | WPRIM | ID: wpr-187084
ABSTRACT

PURPOSE:

This meta-analysis aimed to evaluate the effect of cassia cinnamon (Cinnamomum. cassia and C. aromaticum) on the glycemic response with a focus on the preparation of dehydrated powder and water extract.

METHODS:

We searched Pubmed, Cochrane, EMBASE, Science Direct, and the Korean Studies Information Service System (KISS) through May 2017. In the meta-analysis for the preparation of powder, eight trials reporting fasting blood glucose (FBG), four trials reporting HbA1c, and three trials reporting the postprandial glycemic response were included. For the water extract, six trials reporting FBG and four trials reporting HbA1c were eligible for this study. A random-effects model was used to calculate the pooled effect size.

RESULTS:

Cassia cinnamon powder intake significantly lowered FBG by −1.55 mmol/L (95% CI, −2.45, −0.64; p = 0.001) and the AUC of postprandial blood glucose level by −51.8 mmol/L·min (95% CI, −85.5, −18.1; p = 0.003). There was a significant difference in FBG between water extract of cinnamon and placebo of −0.76 mmol/L (95% CI, −1.09, −0.43; p = 0.000). However, blood HbA1c level was not significantly altered by any preparation of cinnamon. No statistical heterogeneity was observed for any analysis except in the case of FBG for cinnamon powder. Results of funnel plots and Egger's regression suggest a low likelihood of publication bias in all biomarkers (p > 0.05).

CONCLUSION:

According to this meta-analysis, there was possible evidence to support a relationship between cassia cinnamon intake and fasting glucose in both preparation of powder and water extract. Furthermore, new evidence of the health benefits on postprandial glucose regulation of cinnamon powder was obtained.
Subject(s)

Full text: Available Index: WPRIM (Western Pacific) Main subject: Population Characteristics / Blood Glucose / Water / Biomarkers / Cassia / Fasting / Cinnamomum zeylanicum / Publication Bias / Area Under Curve / Cinnamomum aromaticum Type of study: Controlled clinical trial / Prognostic study / Systematic reviews Language: Korean Journal: Journal of Nutrition and Health Year: 2017 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Population Characteristics / Blood Glucose / Water / Biomarkers / Cassia / Fasting / Cinnamomum zeylanicum / Publication Bias / Area Under Curve / Cinnamomum aromaticum Type of study: Controlled clinical trial / Prognostic study / Systematic reviews Language: Korean Journal: Journal of Nutrition and Health Year: 2017 Type: Article