A Case of Anaphylaxis to Oral Minocycline
Journal of Korean Medical Science
;
: 1231-1233, 2010.
Article
in English
| WPRIM
| ID: wpr-187240
ABSTRACT
Minocycline is a semisynthetic tetracycline derivative that is often used in the treatment of acne vulgaris. To date, there has been only one case report of anaphylaxis to minocycline. We report here a case of anaphylaxis to oral minocycline. A 56-yr-old woman visited our hospital after three episodes of recurrent anaphylaxis. We performed an oral challenge test, the standard method for diagnosing drug allergies, with minocycline, one of the drugs she had taken previously. She developed urticaria, angioedema, nausea, vomiting, hypotension, and dyspnea within 4 min and was treated with intramuscular epinephrine, intravenous antihistamine and systemic corticosteroid. However, she presented similar symptoms at 50 min and at 110 min. In prescribing oral minocycline, physicians should consider the possibility of serious adverse reactions, such as anaphylaxis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Administration, Oral
/
Drug Hypersensitivity
/
Anaphylaxis
/
Minocycline
/
Anti-Bacterial Agents
Limits:
Female
/
Humans
Language:
English
Journal:
Journal of Korean Medical Science
Year:
2010
Type:
Article
Similar
MEDLINE
...
LILACS
LIS