A Case of Disulfiram Neuropathy
Journal of the Korean Neurological Association
;
: 682-688, 1995.
Article
in Korean
| WPRIM
| ID: wpr-187815
ABSTRACT
Disulfiram, tetraethylthiuram disulfide, has been used in the clinical treatment of alcoholism since 1948. Aside from the manifestations of a disulfiram-alcohol reaction, disulfiram causes direct toxic side effects including psychiatric, cardiovascular, hematologic and neurologic disorders. The most frequent neurologic side effects are drowsiness, apathy, headache, decreased sexual potency, neuropathy, and optic neuritis. We describe a 26-year-old man who insidiously developed a distal synunetric sensorimotor polyneuropathy after seven years of disulfiram ingestion confirmed by nerve biopsy. He showed nearly complete resolution after the disulfiram was stopped.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Polyneuropathies
/
Sleep Stages
/
Biopsy
/
Optic Neuritis
/
Disulfiram
/
Alcoholism
/
Eating
/
Apathy
/
Headache
/
Nervous System Diseases
Limits:
Adult
/
Humans
Language:
Korean
Journal:
Journal of the Korean Neurological Association
Year:
1995
Type:
Article
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