Depression and Anxiety in the Epileptic Patients: the Association With Demographic and Seizure-Related Variables
Journal of the Korean Neurological Association
;
: 375-383, 2009.
Article
in Korean
| WPRIM
| ID: wpr-188691
ABSTRACT
BACKGROUND:
Depression and anxiety are common psychiatric symptoms in patients with epilepsy, exerting a profound negative effect on health-related quality of life. Several issues, however, pertaining to their association with psychosocial, seizure-related and medication factors, remain controversial. In the present study we have investigated the association of depression and anxiety with various demographic and seizure-related variables in patients with newly-diagnosed and chronic epilepsy.METHODS:
We investigated 80 patients with epilepsy (46.3% males, mean age 36.1+/-11.4 years, range 18~64; mean disease duration, 13.4+/-12.2 years). Depression and anxiety were assessed in the interictal state with the Beck Depression Inventory, 21-item version (BDI-21) and the state and trait subscales of the State-Trait Anxiety Inventory (STAI-S and STAI-T), respectively. The association of depression and anxiety with various variables was investigated using univariate analyses and multiple linear regression analyses.RESULTS:
Duration of epilepsy, the number of side effects and the number of GABAergic anti-epileptic drugs were correlated with depression, together accounting for 25.1% of the variation of the BDI-21. The STAI-S index was significantly associated with occupation status and the number of GABAergic anti-epileptic drugs accounting for 27.4% of the variation of the STAI-S. Finally, the number of side effects was correlated with trait anxiety.CONCLUSIONS:
Our study shows that the duration of epilepsy, occupation status, GABAergic anti-epileptic drugs and the number of side effects are risk factors for the development of depression and/or anxiety.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Anxiety
/
Quality of Life
/
Linear Models
/
Risk Factors
/
Depression
/
Epilepsy
/
Accounting
/
Occupations
Type of study:
Etiology study
/
Prognostic study
/
Risk factors
Limits:
Humans
/
Male
Language:
Korean
Journal:
Journal of the Korean Neurological Association
Year:
2009
Type:
Article
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