A pediatric case of Brugada syndrome diagnosed by fever-provoked ventricular tachycardia / 소아과
Korean Journal of Pediatrics
;
: 374-378, 2014.
Article
in English
| WPRIM
| ID: wpr-188730
ABSTRACT
Brugada syndrome is a rare channelopathy associated with the SCN5A gene that causes fatal ventricular arrhythmias. This case of Brugada syndrome, in which ventricular tachycardia (VT) was provoked by high fever, is the first report in a Korean child. The boy had retinoblastoma of his left eye diagnosed at 16 months of age. After chemotherapy, he contracted a catheter-related infection with a high fever up to 41degrees C leading to monomorphic VT. This was characterized as having right bundle branch block morphology, superior axis deviation, and a heart rate of 212/min. Direct current cardioversion recovered the VT to sinus rhythm after a lack of response to amiodarone and lidocaine. A second attack of VT that was not controlled by cardioversion, however, responded to lidocaine. The baseline electrocardiogram showed a long PR interval and QRS duration, and the patient's grandfather had a history of Brugada syndrome. A mutation in SCN5A was identified in this patient, his father, and his grandfather. The patient was treated with quinidine and followed up for 1 year.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Arrhythmias, Cardiac
/
Quinidine
/
Retinoblastoma
/
Axis, Cervical Vertebra
/
Bundle-Branch Block
/
Electric Countershock
/
Tachycardia, Ventricular
/
Drug Therapy
/
Electrocardiography
/
Brugada Syndrome
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Child
/
Humans
/
Male
Language:
English
Journal:
Korean Journal of Pediatrics
Year:
2014
Type:
Article
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