Urinary Lithiasis in Children : A Single Center Study
Journal of the Korean Society of Pediatric Nephrology
;
: 280-287, 2007.
Article
in Korean
| WPRIM
| ID: wpr-188898
ABSTRACT
PURPOSE:
Urinary lithiasis is uncommon in children, however, it may lead to chronic renal insufficiency and even end stage renal disease. The etiology of stone formation in children is largely unknown; although the most common causes are known to be associated with congenital anomalies of the genito-urinary(G-U) tract, urinary tract infections(UTI), and metabolic diseases.METHODS:
A total of 73 children(malefemale=4231, mean age 6.6+/-5.3 years) presented with urinary lithiasis between Sep. 1998 and Jul. 2007 at Seoul National University Children's Hospital. The medical records were reviewed retrospectively.RESULTS:
The most common presenting symptoms were gross hematuria(28/73, 38%) and flank or abdominal pain(23/73, 32%). The stones were located in the upper urinary tract in 48 patients(66%), in the bladder in 18(24%), and in both the bladder and upper urinary tract in 2 (3%). Congenital anomalies of the G-U tract with/without UTI were detected in 30 children (41%), hypercalciuria with/without hypercalcemia in 15(20%), and other metabolic diseases in 8(11%). In 17 patients(23%), no underlying cause of stone formation was detected. The majority of stones were infected stones(24/36, 67%), which were followed by calcium stones(8/36, 22%), uric acid stones(3/36, 8%), and cystine stones(1/36, 3%). Thirty-four patients(46%) underwent surgical procedures and/or extracorporeal shockwave lithotripsy for stone removal, and 13(18%) passed stones spontaneously with/without medical management. Stones recurred in 6 patients(8%) 4 with neurogenic bladder augmented by ileocystoplasty, 1 with cystinuria, and 1 with unknown etiology.CONCLUSION:
The common causes of urinary lithiasis in children were congenital anomalies of the G-U tract with/without UTI and metabolic disorders including hypercalciuria/hypercalcemia. For the management of stones, minimally invasive procedures should be chosen on the basis of accompanying symptoms and the composition, locations and etiology of stones.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Uric Acid
/
Urinary Tract
/
Urinary Bladder
/
Urinary Bladder, Neurogenic
/
Lithotripsy
/
Medical Records
/
Calcium
/
Retrospective Studies
/
Cystine
Type of study:
Observational study
Limits:
Child
/
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Journal of the Korean Society of Pediatric Nephrology
Year:
2007
Type:
Article
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