Minimal Deviation Adenocarcinoma, Mucinous Type, of the Uterine Cervix: Report of a Case with Extensive Metastasis to the Uterine Corpus and Bilateral Adnexae
Korean Journal of Pathology
;
: 121-125, 2004.
Article
in English
| WPRIM
| ID: wpr-189660
ABSTRACT
Minimal deviation adenocarcinoma is an extremely well differentiated variant of cervical adenocarcinoma, and is frequently misdiagnosed due to its benign-looking histopathological features. A 38-year-old woman was diagnosed as having had a minimal deviation adenocarcinoma in the cervix, metastasizing to the uterine body and bilateral adnexae. She had a history of right salpingo-oophorectomy 3 years ago, and was diagnosed as having a mucinous cystadenoma. Histologically, the tumor cells were so well-differentiated that they appeared to be almost the same as those of the non-neoplastic cervical glands. Similar glands were found in both ovaries and in the left fallopian tube. PAS staining showed a negative or apical positive pattern in the endocervical-like glands. Immunohistochemical studies for CEA, ER/PR, cytokeratin 20, and p53 were negative, but positive for cytokeratin 7. The HPV DNA microarray test was negative. Clinically, this proved to be an advanced, biologically aggressive disease.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Ovary
/
Adenocarcinoma
/
Cervix Uteri
/
Cystadenoma, Mucinous
/
Adenocarcinoma, Mucinous
/
Oligonucleotide Array Sequence Analysis
/
Keratin-20
/
Keratin-7
/
Fallopian Tubes
/
Neoplasm Metastasis
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
Korean Journal of Pathology
Year:
2004
Type:
Article
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