Prevalence of Subjects at a High or Very High Risk of Gastric Cancer in Japan
Gut and Liver
;
: 95-100, 2009.
Article
in English
| WPRIM
| ID: wpr-190164
ABSTRACT
BACKGROUND/AIMS:
The presence of Helicobacter pylori (H. pylori) infection represents a high-risk state of gastric cancer, but the risk is even higher in gastric atrophy. H. pylori stool antigen (HpSA) and serum pepsinogen (PG) tests are useful tools for screening present infection and gastric atrophy, respectively. To determine the prevalence of subjects at a high risk (HpSA+ or PG+) or very high risk (PG+) of gastric cancer in Japan, we applied the two tests to a general population.METHODS:
The subjects included 311 volunteers. We used Meridian HpSA ELISA for the HpSA test and Pepsinogen RIA Beads for the PG test. PG I at 50% of those older than 40 years). Half of the subjects older than 60 years were PG+.CONCLUSIONS:
In Japan, more than 50% of general population aged > or =40 years is at a high risk of gastric cancer, and half of the population aged > or =60 years is at a very high risk.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Atrophy
/
Stomach Neoplasms
/
Enzyme-Linked Immunosorbent Assay
/
Mass Screening
/
Prevalence
/
Helicobacter pylori
/
Pepsinogen A
/
Japan
Type of study:
Etiology study
/
Prevalence study
/
Risk factors
/
Screening study
Limits:
Aged
/
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Gut and Liver
Year:
2009
Type:
Article
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