Successful Treatment of Child Neuro-Behcet's Disease with Infliximab
Journal of Rheumatic Diseases
;
: 209-213, 2014.
Article
in Korean
| WPRIM
| ID: wpr-190174
ABSTRACT
Behcet's disease is a systemic vasculitis, characterized by recurrent oral aphthous ulcers, recurrent genital ulcers, skin lesion, and ocular involvement. Monoclonal antibody to the tumor necrosis factor-alpha (TNF-alpha) is considered as a possible therapeutic approach to achieve clinical improvement, preventing relapse in Behcet's disease refractory to conventional anti-inflammatory drugs or immunosuppressive durgs. We report the use of infliximab, which is one of the TNF-alpha monoclonal antibodies, in a 17-year-old girl with Behcet's disease exhibiting severe mucocutaneous, ocular and neurological involvement refractory to standard treatment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Skin Ulcer
/
Stomatitis, Aphthous
/
Tumor Necrosis Factor-alpha
/
Systemic Vasculitis
/
Infliximab
/
Antibodies, Monoclonal
Limits:
Adolescent
/
Child
/
Female
/
Humans
Language:
Korean
Journal:
Journal of Rheumatic Diseases
Year:
2014
Type:
Article
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