Health Related Quality of Life in Common Variable Immunodeficiency
Yonsei Medical Journal
;
: 603-610, 2012.
Article
in English
| WPRIM
| ID: wpr-190359
ABSTRACT
PURPOSE:
To quantify the health related quality of life in primary immunodeficiency patients. MATERIALS ANDMETHODS:
We used generic health status and general psychological health questionnaires to determine the range of issues that needed to be considered in examining the burden of common variable immunodeficiency (CVID).RESULTS:
The health status of patients with CVID was lower than that observed in normal subjects. Overall, Role-Physical and General Health scales correlated with a poorer clinical status. Surprisingly, the duration of disease did not influence health status. Being female, older, General Health Questionnaire-positive and alexithymic proved to be major risk factors associated with a poor health status. Patients with chronic lung disease and chronic diarrhea had the lowest values on the Medical Outcome Study, Short Form SF-36 (SF-36) scales. Disease severity perception was associated with the General Health Questionnaire and alexithymia status. Limitations in daily activities as a result of lower physical health were the major problems facing common variable immunodeficiency patients.CONCLUSION:
Our data underlined the importance of conducting a periodical health related quality of life assessment on patients with primary antibody deficiencies and, moreover, stressed the necessity of providing psychological support to at risk patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Quality of Life
/
Health Status
/
Chronic Disease
/
Surveys and Questionnaires
/
Common Variable Immunodeficiency
Limits:
Female
/
Humans
/
Male
Language:
English
Journal:
Yonsei Medical Journal
Year:
2012
Type:
Article
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