Some opinions of the natural transform of the diseases in the myelo-proliferative syndrome (MPS)

ABSTRACT

MPS comprised 4 disease's forms, such as Chronic myelogenous leukemia (CLM), polycythemia vera (PV), essential thrombocytothemia (ET) and idiopathic myelofibrosis (IMF). From 1985 to May-2001 at Friendship hospital, authors have followed up a group of 86 patients with MPS and some remarks had been drawn out Some disease's forms of MPS can transform each other, such as +PV transformed in to CML 10.00%; +PV transformed in to ET 16.67%; +IMF transformed in to CML 66.67%; +ET transformed in to CLM 8.0%. Some case in MPS, although have not yet truly transformed, but have some changes, as such +ET with concomitantly increasing erythrocytes 4.0%; +IMF with concomitantly increasing platelets 33.33%; +CML with concomitantly increasing platelets 21.43%; Authors have also mentioned many interesting issues about the way of transformation, the last diagnosis for those disease's forms and the prognosis of these transformations