Usefulness of F-18 FDG PET/CT in Adrenal Incidentaloma: Differential Diagnosis of Adrenal Metastasis in Oncologic Patients / 핵의학분자영상
Nuclear Medicine and Molecular Imaging
;
: 421-428, 2009.
Article
in Korean
| WPRIM
| ID: wpr-190758
ABSTRACT
PURPOSE:
We have evaluated characteristics of adrenal masses incidentally observed in nonenhanced F-18 FDG PET/CT of the oncologic patients and the diagnostic ability of F-18 FDG PET/CT to differentiate malignant from benign adrenal masses. MATERIALS ANDMETHODS:
Between Mar 2005 and Aug 2008, 75 oncologic patients (46 men, 29 women; mean age, 60.8+/-10.2 years; range, 35-87 years) with 89 adrenal masses incidentally found in PET/CT were enrolled in this study. For quantitative analysis, size (cm), Hounsfield unit (HU), maximum standardized uptake value (SUVmax), SUVratio of all 89 adrenal masses were measured. SUVmax of the adrenal mass divided by SUVliver, which is SUVmax of the segment 8, was defined as SUVratio. The final diagnosis of adrenal masses was based on pathologic confirmation, radiologic evaluation (HU<0 benign), and clinical decision.RESULTS:
Size, HU, SUVmax, and SUVratio were all significantly different between benign and malignant adrenal masses.(P < 0.05) And, SUVratio was the most accurate parameter. A cut-off value of 1.0 for SUVratio provided 90.9% sensitivity and 75.6% specificity. In small adrenal masses (1.5 cm or less), only SUVratio had statistically significant difference between benign and malignant adrenal masses. Similarly a cut-off value of 1.0 for SUVratio provided 80.0% sensitivity and 86.4% specificity.CONCLUSION:
F-18 FDG PET/CT can offer more accurate information with quantitative analysis in differentiating malignant from benign adrenal masses incidentally observed in oncologic patients, compared to nonenhanced CT.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Sensitivity and Specificity
/
Adrenal Gland Neoplasms
/
Diagnosis, Differential
/
Neoplasm Metastasis
Type of study:
Diagnostic study
/
Prognostic study
Limits:
Humans
/
Male
Language:
Korean
Journal:
Nuclear Medicine and Molecular Imaging
Year:
2009
Type:
Article
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