The Characteristics of Associative Learning of Reward Approach and Loss Aversion in Schizophrenia / 대한정신분열병학회지
Korean Journal of Schizophrenia Research
;
: 59-65, 2012.
Article
in Korean
| WPRIM
| ID: wpr-191082
ABSTRACT
OBJECTIVES:
Schizophrenia patients have deficits of prediction and learning related to dopaminergic dysfunction. It is hypothesized that there would be different characteristics in associative learning of reward approach and loss aversion between controls and patients.METHODS:
Participants were 23 healthy participants and 20 out-patients fulfilling criteria for schizophrenia according DSM-IV-TR. Using a monetary incentive contingency reversal task, successful learning rates, numbers of trials and errors till learning, numbers of trials of maintaining learning, response times were measured. Characteristics of learning were compared between controls and patients.RESULTS:
Physical anhedonia and PANSS negative symptom scores correlated with the number of trials while loss aversion was maintained. Overall correct response rates were decreased in patient group, particularly during reward approach learning. Patients required more trials and errors to learn reward approach than controls. There were no significant differences in learning performance and reaction times between groups during loss avoidance learning.CONCLUSION:
These results support previous reports of deficits in reward-driven learning in schizophrenia. However, anhedonia and negative symptoms were associated with the preserved function of loss avoidance learning.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Outpatients
/
Reaction Time
/
Reinforcement, Psychology
/
Reward
/
Schizophrenia
/
Avoidance Learning
/
Anhedonia
/
Learning
/
Motivation
Type of study:
Prognostic study
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Schizophrenia Research
Year:
2012
Type:
Article
Similar
MEDLINE
...
LILACS
LIS