Spinal epidural granulocytic sarcoma preceding acute myelogenous leukemia
Journal of Korean Medical Science
;
: 291-296, 1992.
Article
in English
| WPRIM
| ID: wpr-191160
ABSTRACT
A rare case of spinal epidural granulocytic sarcoma (GS) preceding acute myelogenous leukemia is described. A 10-year-old boy presented with lower leg weakness. The initial diagnosis was a histiocytic lymphoma, and he was treated accordingly. No evidence of bone marrow involvement was found at that time. The correct diagnosis of epidural GS was made possible in retrospect by using immunoperoxidase staining for lysozyme fourteen months later when the patient showed the full-blown features of leukemia. This rare tumor should be considered in the differential diagnosis of an epidural mass with cord compression in patients with or even without acute leukemia, because early diagnosis followed by appropriate combined chemotherapy and radiation may obviate surgical intervention and eventually prevent leukemic transformation.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Epidural Neoplasms
/
Leukemia, Myeloid, Acute
/
Leukemia, Myeloid
/
Immunoenzyme Techniques
/
Neoplasms, Second Primary
Type of study:
Screening study
Limits:
Child
/
Humans
/
Male
Language:
English
Journal:
Journal of Korean Medical Science
Year:
1992
Type:
Article
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