The Effect of a Proton-pump Inhibitor in Unexplained Chronic Cough Patients / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases
;
: 137-142, 2006.
Article
in Korean
| WPRIM
| ID: wpr-191193
ABSTRACT
BACKGROUND:
Recent studies have suggested an association between chronic cough and gastroesophageal reflux. Our study aimed to assess the utility of a proton-pump inhibitor in unexplained chronic cough patients.METHODS:
Patients with chronic cough of unknown etiology were evaluated using a chest x-ray, methacholine challenge test, and an empirical trial of postnasal drip therapy. After excluding other potential causes of the cough, forty patients were included in the study and treated for 8 weeks with a proton-pump inhibitor.RESULTS:
Eleven and three patients in the first and second 4 weeks were lost to follow-up, leaving twenty-six patients finally included in the study. Of these patients, two were unimproved, eight partially responded to the proton-pump inhibitor and sixteen responded completely after the 8 week treatment.CONCLUSION:
We suggest that empirical treatment with a proton pump inhibitor in all patients with persistent cough, which is not secondary to asthma or postnasal drip syndrome, represents a practical and simple approach to this ailment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Asthma
/
Thorax
/
Gastroesophageal Reflux
/
Methacholine Chloride
/
Proton Pumps
/
Cough
/
Lost to Follow-Up
Limits:
Humans
Language:
Korean
Journal:
Tuberculosis and Respiratory Diseases
Year:
2006
Type:
Article
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