Combination Therapy of Intraurethral Condyloma Acuminatum with Holmium: YAG Laser and 5-Fluorouracil Instillation / 대한남성과학회지
Korean Journal of Andrology
;
: 36-40, 2004.
Article
in Korean
| WPRIM
| ID: wpr-191916
ABSTRACT
PURPOSE:
Condyloma acuminatum is a common sexually transmitted disease of the external genitalia and anus. Approximately 5% of patients demonstrate urethral involvement. Electrical fulguration or excision using a pediatric resectoscope has been used in the management of such lesions. Holmium(Ho)YAG laser, 5-FU(fluorouracil), or interferon may be helpful in eradicating them. We reviewed the results of intraurethral condyloma acuminatum treatment with HoYAG laser and 5-FU solution. MATERIALS ANDMETHODS:
From January 2001 to July 2002, seven patients with intraurethral condylomata acuminata were enrolled in the study. The mean age of the subjects was 19.5(range 25~43) years. Under local anesthesia with 10% lidocaine spray and jelly, all of the intraurethral lesions were removed with the HoYAG laser followed by coverage with 10mL of 5% 5-FU solution. Intraurethral injection of 5-FU was performed weekly up to six times. Urethroscopy for detection of recurrence was done 3 months after initial laser therapy.RESULTS:
Most patients had multiple intraurethral lesions. Six patients (86%) responded to initial therapy without local recurrence with a mean follow-up of 15.8 (range 9.1-23.2) months. One patient had a recurrence at 2 months.CONCLUSIONS:
We believe that the HoYAG laser plus 5% 5-FU solution is a useful option for the treatment of intraurethral condyloma acuminatum.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Anal Canal
/
Recurrence
/
Condylomata Acuminata
/
Sexually Transmitted Diseases
/
Follow-Up Studies
/
Interferons
/
Laser Therapy
/
Lasers, Solid-State
/
Fluorouracil
/
Genitalia
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Andrology
Year:
2004
Type:
Article
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