A Case of Pyogenic Spondylitis Due to Aggregatibacter aphrophilus / 대한임상미생물학회지
Annals of Clinical Microbiology
;
: 99-103, 2014.
Article
in Korean
| WPRIM
| ID: wpr-192000
ABSTRACT
Aggregatibacter aphrophilus, a normal component of oral cavity flora, mostly causes infective endocarditis and only rarely causes spondylitis; no spondylitis cases have been previously reported in Korea. We report a case of pyogenic spondylitis due to A. aphrophilus without endocarditis. A 64-year-old man was admitted for back pain lasting 3 weeks. There was severe tenderness on lumbar spines but no fever. Laboratory evaluation showed leukocytosis and elevated C-reactive protein. Blood cultures were negative. Magnetic resonance imaging showed psoas abscess and vertebral inflammation. Pus was obtained by computerized tomography-guided aspiration from the psoas abscess and inoculated into blood culture bottles. After 5 days of incubation, growth was detected the isolate was a Gram-negative short rod bacteria identified as A. aphrophilus by the automated system; this was confirmed by 16S ribosomal RNA sequencing. There was no evidence of endocarditis in echocardiography and retinal examination. Back pain persisted despite 8 weeks of antibiotic treatment, so vertebral corpectomy was performed. A. aphrophilus, a rare cause of pyogenic spondylitis, can induce spondylitis without endocarditis. If a patient with pyogenic spondylitis shows negative routine bacterial cultures, fastidious organisms such as A. aphrophilus should be suspected and the blood culture bottles could be used.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Retinaldehyde
/
Spine
/
Spondylitis
/
Suppuration
/
Bacteria
/
C-Reactive Protein
/
Magnetic Resonance Imaging
/
RNA, Ribosomal, 16S
/
Echocardiography
/
Psoas Abscess
Limits:
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Annals of Clinical Microbiology
Year:
2014
Type:
Article
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