Transient Left Ventricular Dysfunction After Percutaneous Patent Ductus Arteriosus Closure in Children
Korean Circulation Journal
;
: 596-600, 2008.
Article
in English
| WPRIM
| ID: wpr-192091
ABSTRACT
BACKGROUND AND OBJECTIVES:
The goal of this study was to assess changes in left ventricular (LV) function and to identify pre-closure factors associated with LV dysfunction {fractional shortening (FS) below 29%} after transcatheter patent ductus arteriosus (PDA) closure. SUBJECTS ANDMETHODS:
Forty-three pediatric patients with PDAs underwent cardiac catheterization for hemodynamic studies and intervention. Doppler echocardiography was performed at pre-closure, post-closure, and follow-up.RESULTS:
S' and A' of the septum and mitral annulus were significantly decreased at post-closure and follow-up, respectively. In five of eight patients with Qp/Qs ratios over 1.60 and Pp/Ps ratios over 0.32 at pre-closure, the FS was decreased below 29% at post-closure. Qp/Qs ratio over 1.60 and Pp/Ps ratio over 0.32 at pre-closure had a sensitivity of 86% and a specificity of 84% for predicting FS to be below 29% at post-closure.CONCLUSION:
Larger amounts of pre-closure left-to-right shunting and higher pulmonary artery pressure were associated with an increased likelihood of FS <29% after closure. The results of this study suggest that serial assessments of ventricular function are needed after PDA occlusion in patients with high Qp/Qs and Pp/Ps ratios.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pulmonary Artery
/
Cardiac Catheterization
/
Echocardiography, Doppler
/
Follow-Up Studies
/
Ventricular Function
/
Sensitivity and Specificity
/
Ventricular Dysfunction, Left
/
Ventricular Dysfunction
/
Ductus Arteriosus, Patent
/
Cardiac Catheters
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Limits:
Child
/
Humans
Language:
English
Journal:
Korean Circulation Journal
Year:
2008
Type:
Article
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