Localized periorbital edema as a clinical manifestation of sulfite sensitivity
Journal of Korean Medical Science
;
: 356-357, 1996.
Article
in English
| WPRIM
| ID: wpr-192894
ABSTRACT
Sulfite is commonly used in pharmaceuticals as a preservative. We report a unique clinical presentation of localized periorbital edema on the left eye after administration of sulfite-containing dexamethasone. The patient's sulfite sensitivity was confirmed by sulfite oral provocation test periorbital edema on the same site developed after ingestion of 200 mg sodium bisulfite. She was non-atopic and did not complain of any respiratory symptoms. Allergy skin prick test with 100 mg/ml sodium bisulfite showed a negative result. She also has aspirin-sensitive urticaria which was confirmed by oral provocation test. In conclusion, sulfite can induce a localized periorbital edema, an uncommon manifestation in sensitive patients. Further investigations are needed to clarify the pathogenetic mechanisms.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Orbital Diseases
/
Skin Diseases
/
Sulfites
/
Allergens
/
Edema
/
Middle Aged
Type of study:
Diagnostic study
Limits:
Female
/
Humans
Language:
English
Journal:
Journal of Korean Medical Science
Year:
1996
Type:
Article
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