Intravenous Lidocaine Prior to Extubation Reduces Emergence Agitation and Cough in Pediatric Adenotonsillectomy under Sevoflurane Anesthesia / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 458-462, 2007.
Article
in Korean
| WPRIM
| ID: wpr-193267
ABSTRACT
BACKGROUND:
Sevoflurane is widely used to ambulatory pediatric anesthesia. But, sevoflurane is associated with a high incidence of emergence agitation in children. In this study, we examined the effect of single intravenous lidocaine prior to extubation on emergence agitation and cough in children undergoing adenotonsillectomy.METHODS:
All patients received a standardized anesthetic regimen with 2~3% sevoflurane in 50% O2/N2O after anesthetic induction with intravenous glycopyrrolate 0.004 mg/kg, thiopental 5 mg/kg and vecuronium 0.1 mg/kg. In a double-blinded trial, 120 children (3~9 years) were randomly assigned to receive normal saline 0.1 ml/kg (Group C), 1% lidocaine 1 mg/kg (Group L1) or 2% lidocaine 2 mg/kg (Group L2), at 1 min after beginning of spontaneous respiration. After extubation, the sedation score and the incidence of agitation and cough were recorded.RESULTS:
The incidence of agitation and cough in Group L1 and L2 were significantly less than Group C (P or = 2) than Group C. More patients in Group L1 were in deeper sedation than Group L2 and C at 10 min after arrival at PACU.CONCLUSIONS:
We conclude that intravenous lidocaine prior to extubation reduces emergence agitation and cough after sevoflurane anesthesia in children undergoing adenotonsillectomy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Respiration
/
Thiopental
/
Vecuronium Bromide
/
Incidence
/
Cough
/
Dihydroergotamine
/
Glycopyrrolate
/
Anesthesia
/
Lidocaine
Type of study:
Incidence study
/
Prognostic study
Limits:
Child
/
Humans
Language:
Korean
Journal:
Korean Journal of Anesthesiology
Year:
2007
Type:
Article
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