Predictive Factors for Long-term Clinical Outcomes in Patients with Variant Angina / 대한내과학회지
Korean Journal of Medicine
;
: 522-530, 2013.
Article
in Korean
| WPRIM
| ID: wpr-193314
ABSTRACT
BACKGROUND/AIMS:
The incidence of variant angina (VA) is relatively high in Korea compared with western countries, but its long-term clinical outcomes are not well defined.METHODS:
Patients who underwent ergonovine provocation tests at the cardiac catheterization laboratory of Chonnam National University Hospital between 1996 and 2011 were enrolled in this study (n = 1162). Of them, 686 patients with positive ergonovine provocation tests were divided into two groups patients with cardiac events (Group I 153 patients, 52.4 +/- 11.0 years, M F = 103 50) and those without (Group II 533 patients, 51.6 +/- 10.7 years, M F = 350 183). The mean follow-up duration was 40.2 +/- 38.0 months. Cardiac events were defined as cardiac death, recurrent ischemia, rehospitalization, myocardial infarction, and follow-up angiography. Clinical findings, laboratory and coronary angiographic characteristics were compared between the groups.RESULTS:
A history of smoking was more common in Group I than in Group II (45.8% vs. 36.3%, p = 0.037). The levels of low-density lipoprotein cholesterol (119.4 +/- 35.3 vs. 111.1 +/- 32.2 mg/dL, p = 0.010) were higher in Group I than in Group II. According to Cox proportional hazard regression analysis, the major predictive factor for cardiac events during clinical follow-up was smoking (HR 1.80, 95% CI 1.036-3.126, p = 0.037).CONCLUSIONS:
A history of smoking was the only independent risk factor for cardiac events during a long-term clinical follow-up in Korean patients with variant angina.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Smoke
/
Coronary Artery Disease
/
Angiography
/
Cardiac Catheterization
/
Smoking
/
Cholesterol
/
Incidence
/
Risk Factors
/
Follow-Up Studies
/
Death
Type of study:
Etiology study
/
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2013
Type:
Article
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