Histological comparison of endoscopic forceps biopsy with endoscopic mucosal resection in the gastric lesions / 대한내과학회지
Korean Journal of Medicine
;
: 600-608, 2006.
Article
in Korean
| WPRIM
| ID: wpr-193441
ABSTRACT
BACKGROUND:
The correct histological diagnosis of a gastric adenoma is important, because an adenoma has been reported to be a precancerous lesion and is associated with focal gastric carcinoma. However, there is some discrepancy between the histology of a forceps biopsy and that of the endoscopic mucosal resection. This study compared the histological findings of a gastric mucosal lesion in the specimens of a forceps biopsy and an endoscopic mucosal resection.METHODS:
88 cases of gastric mucosal lesions, which had been removed by the endoscopic mucosal resection, were reviewed retrospectively. All the patients had undergone a forceps biopsy before the endoscopic mucosal resection. The histological findings of the specimens by a forceps biopsy were compared with those by resection.RESULTS:
The histological findings were accordant at 52 of the 88 cases (59.1%). Among the 71 cases with adenoma or gastritis in the biopsied specimens, 13 cases (18.3%) were finally diagnosed with gastric cancer in the resected specimens. Among all the gastritis and adenomas determined by the forceps biopsy, the high-risk groups for adenocarcinomas were characterized by the following endoscopicfindings:
red-colored and depressed lesions.CONCLUSIONS:
Biopsy specimens may not be representative of the entire lesion. Therefore, an endoscopic resection of a gastric mucosal lesion is needed for making an accurate histological diagnosis and treatment if adenomas such as red-colored or depressed lesions are suspected.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Stomach Neoplasms
/
Surgical Instruments
/
Biopsy
/
Adenocarcinoma
/
Adenoma
/
Retrospective Studies
/
Diagnosis
/
Gastritis
Type of study:
Diagnostic study
/
Observational study
Limits:
Humans
Language:
Korean
Journal:
Korean Journal of Medicine
Year:
2006
Type:
Article
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